Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp356 | Osteoporosis: treatment | ECTS2014

Changes in lumbar spine QCT, DXA and TBS with denosumab, alendronate or placebo in postmenopausal women with low bone mass

Thomas Thierry , Cheung Angela M , Shane Elizabeth , Zanchetta Jose R , Kearns Ann , Hans Didier , Lin Celia J F , Austin Matthew , Libanati Cesar

Patients with osteoporosis require treatment with therapies that reduce the risk of fracture which at the spine is significantly influenced by bone microarchitecture. Quantitative computed tomography (QCT) and dual X-ray absorptiometry (DXA) allow measurement of bone mineral density (BMD), a known indicator of fracture risk. Trabecular bone score (TBS) is a novel gray-level measurement derived from spine DXA image texture that is related to microarchitecture and associates wit...